Chemical

The cosmetic industry makes use of a series of ingredients, including phospholipids, vitamins and squalene, that will demand a chromatographic separation and purification step in the manufacturing process.

Zeochem’s ZEOprep range of silica gels offers well-proofed stationary phases which are widely used in the industrial scale production of such materials. The broad variety of different silicas available, as well as batch sizes adapted to customers’ processes and demand, allow us to meet many kinds of requirements, whatever the target material may be. High yields, purity and reproducibility are as important as process safety and strict QA requirements, all of which are met when using ZEOprep silica gels.

Zeochem’s Research & Development departments in Switzerland and the U.S. have built decades of knowledge within topics such as:

• NMR Spectroscopy
• Isotopic Labeling
• Molecular Sieves
• Specialty Zeolites
• Chromatography Gels

The knowledgeable and experienced members of our research and development team provide support in creating innovative, market-leading products. Team members are committed to supporting and optimizing manufacturing processes. Our team also offers in-house method development services for chromatographic purification applications.

Athletes and sports enthusiasts have driven apparel manufacturers to innovate their product lines since the 1980s. More recently, both groups have favored technologies that make them more comfortable in active-wear as this apparel has become more commonplace in today’s fashion. The technologies not only include more breathable and perspiration control technology but, thanks to ZEOflair type of adsorbents, also an effective body odor control. ZEOflair adsorbents can be incorporated into apparel manufacturing processes (both clothing and footwear) for true odor removal functionality, not odor masking. Given ZEOflair’s proven success in personal care formulations and VOC (volatile organic compound) abatement markets removing odor-causing compounds, it is not surprising body odor control through apparel delivery method has become more broadly accepted.

ZEOflair products offer the following advantages to sports apparel manufacturers:

• Odor removal to virtually imperceptible levels due to its organophilic properties
• High hydrophobic nature which helps retain its adsorption odor capacity in wet conditions (perspiration and apparel laundering)
• Choice of ZEOflair products to truly target body odor types while meeting the needs of manufacturing demands

ZEOflair adsorbents can be used for body odor control in baby diapers, adult incontinence products, feminine hygiene (sanitary napkins), body wipes and other products that are not knitted or woven.

Incorporation of ZEOflair adsorbents during the nonwovens’ manufacturing process is a natural progression in today’s consumer market where odor removal or elimination is expected and demanded. As the elderly population grows around the world, the adult incontinence subcategory is predicted to increase. ZEOflair adsorbents offer the ability to physically remove urine, fecal and other body odors to imperceptible levels with virtually no potential of changing the odors as the result of chemical reaction by-products.

ZEOflair products offer the following advantages to makers of nonwovens:

• Odor removal to virtually imperceptible levels due to its organophilic properties
• High hydrophobic nature which helps retain its adsorption odor capacity in wet conditions
• Choice of ZEOflair products to truly target the types of body odors while meeting the needs of the manufacturing demands

Food/beverage and pharmaceutical manufacturers demand sophisticated packaging that protects the integrity of their products through the various distribution channels. The products integrity (taste or odor) can be impacted by external VOCs and other permeable compou'nds the packaged goods are exposed to in the outside environment (e.g., fuel, detergents, printing inks, adhesives, etc.). Also, the products’ integrity can be impacted by the manufacturing processes of the packaging materials generating off-flavor/taste compounds. For example, the polymeric materials may undergo thermo-oxidative degradation, and there could be interaction with the other additives used in the polymers.

ZEOflair adsorbent powders can be incorporated into packaging at small concentration levels as additional protection for various food/beverage or pharmaceutical packaging material in single or multiple layers to provide a consistent food/beverage product taste/odor regardless of the packaging material’s sourcing and storage history.

For the purification of peptides, insulin (analogues) and oligonucleotides, it is often difficult to use methods similar to those applied in the purification of other organic compounds, mainly due to their complexity. Purification methods usually utilize various principles of chromatography such as ion exchange chromatography and medium or high-pressure reversed-phase chromatography.

Due to increasing government and public pressure to decrease costs of medicines, the purification process should be as simple as possible and contain a minimum of steps. However, the reality is that by using today's classical ion-exchange and/or reversed-phase purification methods, multiple steps are still required to achieve the desired purity. Of course, this has a huge impact on the recovery (yield). Besides this, more organic solvent must be used – all resulting in an inefficient, costly purification process.

ZEOsphere DRP Mixed-Mode materials can substantially improve the selectivity of charged molecules from the adsorption on the hydrophobic sites and repulsion on the charged sites.

This enhanced selectivity leads to desired purity more quickly and will considerably increase the recovery (yield). Because ZEOsphere DRP Mixed-Mode materials can work with low organic solvent conditions, a decrease in organic solvent usage is obtained.

ZEOsphere DRP Mixed-Mode products are today’s answer to improve compound purification and to considerably lower production costs.